Figure 2
Photographs of skin, PET/CT scan, and bone marrow biopsy, pre– and post–SL-401. (A) Involved skin of patient 7 photographed before treatment and 4 months after treatment. (B) PET/CT images for patient 6 scanned before treatment and 1 month after treatment, demonstrating enlarged and PET-avid left inguinal node (1.2 × 1.6 cm; standardized uptake value Max 3.5) and right inguinal node (0.7 × 1 cm; standardized uptake value 2.3) before treatment. These inguinal nodes regressed and were no longer PET-avid at 1 month after treatment. (C) Immunostaining for CD123 on a bone marrow aspirated from patient 1 before treatment and at 1 month after treatment. Pretreatment showed 10% positive cells and after therapy showed <1% to 2% positive cells. Magnification pretreatment microphotograph is ×20; magnification post-treatment microphotograph is ×40.

Photographs of skin, PET/CT scan, and bone marrow biopsy, pre– and post–SL-401. (A) Involved skin of patient 7 photographed before treatment and 4 months after treatment. (B) PET/CT images for patient 6 scanned before treatment and 1 month after treatment, demonstrating enlarged and PET-avid left inguinal node (1.2 × 1.6 cm; standardized uptake value Max 3.5) and right inguinal node (0.7 × 1 cm; standardized uptake value 2.3) before treatment. These inguinal nodes regressed and were no longer PET-avid at 1 month after treatment. (C) Immunostaining for CD123 on a bone marrow aspirated from patient 1 before treatment and at 1 month after treatment. Pretreatment showed 10% positive cells and after therapy showed <1% to 2% positive cells. Magnification pretreatment microphotograph is ×20; magnification post-treatment microphotograph is ×40.

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