Figure 5
Figure 5. CD14+HLA-DRlow/− monocytes correlated with immunosuppressive functions. (A) The percentage of CD14+HLA-DRlow/− monocytes found in peripheral blood of NHL patients is plotted against the in vitro T-cell proliferation response in allogeneic mixed lymphocyte reaction with these NHL monocytes (1:10 monocyte/T-cell ratio; Figure 1B). (B) Similarly, the percentage of CD14+HLA-DRlow/− monocytes in NHL patients was plotted against the ability of these NHL monocytes to differentiate into mature dendritic cell cultures (Figure 2C). (C) The percentage of CD14+HLA-DRlow/− monocytes was plotted against the peripheral blood absolute lymphocyte count as determined using TruCount flow tubes (left panel, n = 25 for control and lymphoma samples). Decreased lymphocyte count in lymphoma patients was correlated to increased percentage of CD14+HLA-DRlow/− monocytes. Statistically significant P value is show between groups. P value for statistically significant correlation.

CD14+HLA-DRlow/− monocytes correlated with immunosuppressive functions. (A) The percentage of CD14+HLA-DRlow/− monocytes found in peripheral blood of NHL patients is plotted against the in vitro T-cell proliferation response in allogeneic mixed lymphocyte reaction with these NHL monocytes (1:10 monocyte/T-cell ratio; Figure 1B). (B) Similarly, the percentage of CD14+HLA-DRlow/− monocytes in NHL patients was plotted against the ability of these NHL monocytes to differentiate into mature dendritic cell cultures (Figure 2C). (C) The percentage of CD14+HLA-DRlow/− monocytes was plotted against the peripheral blood absolute lymphocyte count as determined using TruCount flow tubes (left panel, n = 25 for control and lymphoma samples). Decreased lymphocyte count in lymphoma patients was correlated to increased percentage of CD14+HLA-DRlow/− monocytes. Statistically significant P value is show between groups. P value for statistically significant correlation.

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