Exacerbated BM mobilization in jam-b deficient mice. (A) The graphs show the mobilization indexes for the indicated subsets after AMD 3100 induced-mobilization in jam-b deficient mice (black bars) compared with control animals (white bars). (B) The number of circulating progenitor cells mobilized in the blood of jam-b deficient (black bar) and control mice (white bar) 3 hours after AMD3100 treatment is shown. (C) The mobilization indexes for the indicated subsets after Cy/G-CSF induced-mobilization in control (white bars) and jam-b deficient mice (black bar) are shown. (D) The frequencies of LSK, LT-HSC (LSK CD34^Neg), and LSK CD34^Pos cells after AMD 3100 induced-mobilization in the bone marrow of control (white bars) and jam-b deficient mice (black bars) are shown. Results are representative of at least 3 independent experiments with at least 5 mice per group (*P < .05; **P < .01; ***P < .001).