Monocytes control CD11b^hiCD27^low NK-cell numbers. (A) Frequency of CD115⁺CD11b⁺ monocyte and expression of CD11b and CD27 in NKp46⁺CD3⁻ NK cells in the spleen of control (left panels) and AP20187-treated (right panels) MaFIA mice. (B) Mean frequency ± SD of spleen CD115⁺CD11b⁺ monocytes, NKp46⁺CD3⁻ NK cells, CD11b^hiCD27^low NK cells, CD11b^hiCD27^hi NK cells, and CD11b^lowCD27^hi NK cells, of 3 experiments with 4 mice per experiment. (C) CD115⁺CD11b⁺ monocyte and of CD11b⁺CD27^low NK-cell frequency in the spleen of control C57BL/6 mice or mice injected with CSF-1. Data are mean ± SD of 2 independent experiments with 3 mice per group.