Rapid and transient expression of IFN genes induced by LPS in MDDCs. (A) Expression of IFN-β and IFN-λ1 mRNA in LPS-stimulated MDDCs. The y-axis represents fold induction over mRNA expression in resting cells. Representative data of 2 experiments each performed in triplicate are shown. (B) PolII recruitments to the promoter/TSS regions of IFN-β. Data shown are the mean + SEM from 3 experiments conducted in the cells from independent donors, each nor-malized against the signal generated by the same primer set using no antibody control sample.