Putative DNA regulatory sequences enriched in and depleted from promoters bound by EZH2 binding in GC B cells. The first column shows the DNA motifs discovered by FIRE as underrepresented (top 3 motifs) and overrepresented (remaining motifs) in EZH2-bound promoters. The second column indicates the fold over/underrepresentation of each motif in EZH2-bound promoters versus nonbound promoters. The third column shows enrichment and depletion P values, calculated using the hypergeometric distribution. The last column shows motif names, when they could be identified using DNA motif databases such as TRANSFAC or JASPAR. PRE-like sequences were identified based on their similarity to Drosophila PREs.