microRNA signatures associated with 17pDEL in patients with CLL. (A) The definitions of patient categories. (B) The ratios and P values were obtained by applying the t test in the 7 studied miRNAs among the patients with CLL, classified according to the patients' properties on FISH and KARYO. (C) Clusters of differentially expressed miRNAs. Unsupervised clustering was performed on 104 patients with qRT-PCR expression of miR-15a, miR-21, miR-34a, miR-155, miR-181b, and miR-497. Single linkage and the Euclidean distance metric were used.