Figure 2
Figure 2. Quantitative analysis of thrombus deposition on combinations of synthetic triple-helical peptide surfaces under shear conditions. Image analysis of platelet deposition and thrombus formation yielded different parameters of platelet adhesion and thrombus formation after perfusion of DiOC6-labeled whole blood over peptide-coated surfaces at the given shear rates for 5 minutes; n = 6 or 7. (A) Thrombus or platelet surface coverage (%). (B) Mean thrombus height (μm). Data are mean ± SEM. Shear rates: indicates 100s−1; , 300s−1; , 1000s−1; and ▭, 3000s−1.

Quantitative analysis of thrombus deposition on combinations of synthetic triple-helical peptide surfaces under shear conditions. Image analysis of platelet deposition and thrombus formation yielded different parameters of platelet adhesion and thrombus formation after perfusion of DiOC6-labeled whole blood over peptide-coated surfaces at the given shear rates for 5 minutes; n = 6 or 7. (A) Thrombus or platelet surface coverage (%). (B) Mean thrombus height (μm). Data are mean ± SEM. Shear rates: indicates 100s−1; , 300s−1; , 1000s−1; and ▭, 3000s−1.

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