Prophylactic thrombolysis by scFv/uPA-T in arterial thrombosis. Panels A (saline), B (uPA), C, and D (scFv/uPA-T) show typical tracings of blood flow in the FeCl₃ model of carotid artery injury. Each square on the time axis equals 200 seconds. Panel E shows analysis of the data collected from each group presented as percent of the pre-injury level of blood flow in the carotid artery during the first 30 minutes after induction of injury in mice treated with uPA or scFv/uPA-T 1 hour before injury. N = 6 per group, P < .05.