Epo stimulates Stat5 phosphorylation in the injured vessel wall. Stat5 phosphorylation was investigated by immunohistochemical staining of sections from ligated carotid arteries of mice treated with solvent (A), 150 IU/kg Dynepo (B), or 500 IU/kg Dynepo (C). Representative pictures are shown, and were captured with bright-field microscopy at an original magnification of ×200. (D) The percentage of total intima surface that stained positive for phosphorylated Stat5. Mean and SEM of 4 sections per treatment group are shown. Student t test versus control: **P < .01.