Graft morphology. (A) Histologic appearance (top, ×5; scale bar, 400 μm; bottom, ×20; scale bar, 100 μm) of islets in control pancreas, BM, and liver 1 year after transplantation. (B) Fractional β-cell area, islet size, islet composition, β-cell proliferation, and nucleus density of insulin-positive area in mice reaching normoglycemia after islet transplantation in BM (n = 6) and liver (n = 6) 1 year after islet infusion, and in the pancreas of control mice (n = 6). Data are expressed as mean ± SD. Statistical analysis was performed using 1-way ANOVA test, followed by Bonferroni post hoc t test. *P < .01 versus control; §P < .05 versus intraliver.