Rescue of DAF^−/−/Crry^−/−/C3^−/− mouse platelets by retroviral transgenic expression of Crry. (A) Tracking by FACS of the survival of nontransgenic (population X) and Crry-transgenic (population Y) DAF^−/−/Crry^−/−/C3^−/− platelets in WT recipients. Donor platelets were labeled with CFSE and were distinguishable from endogenous WT platelets (population Z). (B) Plot of elimination kinetics of populations X and Y platelets in panel A. The percentage of platelets remaining at each time point was normalized to the percentage of platelets remaining at 10 minutes after transfusion.