αDEC-205-EBNA1 in combination with poly(I:C) induces EBNA1-specific T-cell responses in bulk PBMCs. PBMCs from blood donors were pulsed with medium, 5 μg/mL αDEC-205-EBNA1, or isotype-EBNA1 using poly(I:C) as an adjuvant and with 10 U/mL IL-2. EBNA1-specific (A) IFN-γ production on day 9 and (B) proliferation by T cells on day 15 were determined as in Figure 1 for 6 different donors. Horizontal lines represent medians.