Comparison of chromosomal imbalances detected by matrix-CGH in pediatric (≤14 years, n = 33) and adult (>18 years, n = 17) mBL. Every vertical bar on the plots represents a CGH clone in its genomic position. The green and red bars show relative frequencies of gains and losses, respectively. The heights of the red bars are given a negative value for clarity. Panel A shows the relative frequency of genomic imbalances in pediatric mBL (≤14 years). Panel B refers to the population of adult mBL (>18 years). Panel C illustrates the discrepancies in the frequency of genomic aberrations between the patient groups from Panel A and B with the corresponding chi-square statistics. The chi-square statistics for losses are shown with a negative sign. Clones with more than 10% missing values or having 5 or fewer aberrations overall are not shown.