Figure 3
Relationship between urinary II-dehydro- TXB2 levels and their potential determinants in polycythemia vera patients. (A) Correlation between VWF levels and urinary 11-dehydro-TXB2 excretion in 29 polycythemia vera patients according to quartiles of ECFCs. ● represents subjects in the first and second quartiles for ECFC number. ○ represent subjects in the third and fourth quartiles for ECFC number. ¦ and  mark the boundaries of median values of both VWF and 11-dehydro-TXB2. (B) Urinary 11-dehydro-TXB2 levels according to quartiles of ECFC number in polycythemia vera patients. Box and whisker plots of urinary 11-dehydro-TXB2 levels divided according to quartiles of ECFC number. , representing the 95th percentile of 11-dehydro-TXB2 values in the control group, discriminates subjects with low versus high 11-dehydro-TXB2 values. Overall significance (by Kruskal-Wallis test): P = .043. (C) ADMA levels in polycythemia vera patients, according to 11-dehydro-TXB2 values below or above the 95th percentile of control values. Box and whisker plots of plasma ADMA levels in PV patients, stratified according to 11-dehydro-TXB2 values below or above the 95th percentile of 11-dehydro-TXB2 values in the control group.

Relationship between urinary II-dehydro- TXB2 levels and their potential determinants in polycythemia vera patients. (A) Correlation between VWF levels and urinary 11-dehydro-TXB2 excretion in 29 polycythemia vera patients according to quartiles of ECFCs. ● represents subjects in the first and second quartiles for ECFC number. ○ represent subjects in the third and fourth quartiles for ECFC number. ¦ and mark the boundaries of median values of both VWF and 11-dehydro-TXB2. (B) Urinary 11-dehydro-TXB2 levels according to quartiles of ECFC number in polycythemia vera patients. Box and whisker plots of urinary 11-dehydro-TXB2 levels divided according to quartiles of ECFC number. , representing the 95th percentile of 11-dehydro-TXB2 values in the control group, discriminates subjects with low versus high 11-dehydro-TXB2 values. Overall significance (by Kruskal-Wallis test): P = .043. (C) ADMA levels in polycythemia vera patients, according to 11-dehydro-TXB2 values below or above the 95th percentile of control values. Box and whisker plots of plasma ADMA levels in PV patients, stratified according to 11-dehydro-TXB2 values below or above the 95th percentile of 11-dehydro-TXB2 values in the control group.

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