Figure 6
Figure 6. IL-17 is not critical for AIHA development in IL-2–KO mice. (A) Survival plots of WT, IL-2–KO, IL-17–KO, and IL-2/IL-17–KO mice. (B) Hematocrit (HCT) values were measured from terminal blood draws. (C) RBCs were stained with anti–mouse IgM or IgG-FITC to evaluate the level of bound anti-RBC antibodies. (D) Bar graphs represent the number (×10−6) of total LN and CD4+ T cells at 3 to 4 weeks. Circles represent individual mice. Bar graphs represent mean plus or minus SD; n = 5 to 9 mice per genotype and time point. **P < .005; ***P < .05.

IL-17 is not critical for AIHA development in IL-2–KO mice. (A) Survival plots of WT, IL-2–KO, IL-17–KO, and IL-2/IL-17–KO mice. (B) Hematocrit (HCT) values were measured from terminal blood draws. (C) RBCs were stained with anti–mouse IgM or IgG-FITC to evaluate the level of bound anti-RBC antibodies. (D) Bar graphs represent the number (×10−6) of total LN and CD4+ T cells at 3 to 4 weeks. Circles represent individual mice. Bar graphs represent mean plus or minus SD; n = 5 to 9 mice per genotype and time point. **P < .005; ***P < .05.

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