Time to progression and overall survival. (A) Kaplan-Meier plot for time to progression (TTP). The vertical axis represents the proportion of patients who are alive and progression-free from first dose of study drug. The horizontal axis represents time in weeks. (B) Kaplan-Meier plot for overall survival (OS). The vertical axis represents the proportion of patients who are alive. The horizontal axis represents the time in weeks from first dose of study drug.