Effect of Fas triggering on the proliferative response of IL-7–treated T cells to self-antigens. IL-7–treated or freshly isolated T cells of noninfected donors were cultured in the presence of autologous dendritic cells. Fas receptors were triggered by recombinant FasL. Proliferation of freshly isolated (open symbols) or IL-7–pretreated (closed symbols) CD4⁺ (A) or CD8⁺ (B) T cells was analyzed in response to autologous DCs and IL-7 or to IL-7 only. Recombinant Fas-L was administrated at different concentrations to the cultures. Representative results of 3 independent experiments are shown.