Curcumin affects hematologic parameters of iron in mice fed a low-iron diet. Serum iron, transferrin saturation, hemoglobin, and hematocrit were measured in mice fed different concentrations of dietary iron containing either 0% or 2% curcumin. Shown are means and SD; n = 5. Curcumin caused a statistically significant reduction in all blood parameters in mice fed 5 mg iron (P ≤ .008).