PILAR encodes a new lymphocyte transmembrane molecule. (A) PILAR gene spans 5 exons encoding a predicted transmembrane molecule that contains a truncated C-type lectin domain in the extracellular region. (B) PILAR alignment with EU095394 and the 2 closest human molecules: Leukocyte markers CD69 and CLEC2D. (C) TaqMan analysis of the expression of PILAR in 10 different human tissues. (D) PILAR is predominantly expressed by naive lymphocyte, but not by myeloid cells. These data are representative of DCs from 2 different donors.