Figure 1.
Figure 1. Evaluation of the sensitivity of Fanca–/– and Fancg–/– myeloid progenitors to IFN-γ. Methylcellulose cultures that promote the growth of myeloid progenitors from FA-deficient bone marrow were established containing a range of concentrations of IFN-γ in triplicate wells. The respective genotypes are indicated. Data represent the mean ± standard error of the mean (SEM) of 4 independent experiments. *P < .01 comparing the IFN-γ–dependent reduction in myeloid progenitors of Fancc–/–, Fanca–/–, and Fancg–/– myeloid progenitors to wild-type controls using analysis of variance.

Evaluation of the sensitivity of Fanca/ and Fancg/ myeloid progenitors to IFN-γ. Methylcellulose cultures that promote the growth of myeloid progenitors from FA-deficient bone marrow were established containing a range of concentrations of IFN-γ in triplicate wells. The respective genotypes are indicated. Data represent the mean ± standard error of the mean (SEM) of 4 independent experiments. *P < .01 comparing the IFN-γ–dependent reduction in myeloid progenitors of Fancc/, Fanca/, and Fancg/ myeloid progenitors to wild-type controls using analysis of variance.

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