Effects of p38 inhibitor on cytokine expression and production by myeloma patient–derived MoDC progenitor cells. (A) RT-PCR detecting mRNA expression for IL-6, IL-10, and TGF-β1 in day-2–cultured cells from a myeloma patient. Representative results of 4 independent experiments are shown. ELISA detecting (B) IL-6 or (C) TGF-β1 in the supernatants of day-3 cultures of the cells. Shown are the mean ± SD of the results obtained from tested myeloma patients (n = 5 for IL-6, and n = 3 for TGF-β1). *P values less than .05.