Nuclear-targeted FAA is fully functional in complementing MMC sensitivity. (A) Schematic representation of FAA-NLS and FAA-mutNLS. (B) (see page 2232) Visualization of FAA-NLS transiently expressed in HeLa cells by immunofluorescence microscopy. (C) Western blot showing the stable expression of FAA-NLS and FAAmutNLS in HSC72 cells. (D) MMC sensitivity assays of the HSC72-derived stable transfectants. (□), Control; (▪), FAA; (•), FAA-NLS; (○), FAA-mutNLS. A representative experiment is shown.