Cumulative incidence of grade III-IV acute GVHD of 165 patients who received cyclosporine/methotrexate, 17.1% (◊) and 164 patients who received tacrolimus/methotrexate 13.3% (□); absolute difference = 3.8%, 95% CI interval = −12.1 to 4.5 (P = .2, Wilcoxon).