Survival function estimates of BCL-6 gene mutations in PT-LPDs. Formal analysis of survival (Kaplan-Meier estimate) with regard to the presence or absence of BCL-6 gene mutations is shown. There was a statistically significant (P = .02) decrease in time to death in the patients with PT-LPDs containing BCL-6 gene mutations. The continuous line indicates a wild-type BCL-6 as assessed by SSCP, and the discontinuous line indicates a mutant BCL-6.