Fig. 1.
Fig. 1. CD8 expression in T-cell expansions. / T-cell expansions from 27 age-matched donors were compared with 22 patients with MM. The data of patients with MM have been published previously5 and were reanalyzed and reported again here for comparison. Cells were gated for either CD8−CD3+ (panels A through D) or CD8+CD3+ T cells (panels E through H) before calculation of the percentage of cells expressing each Vβas a function of either total CD3+ T cells (panels A through B and E through F), CD8−CD3+ (panels C and D), or CD8+CD3+ (panels G and H). Horizontal bars represent 3 SD above the means for the age-matched control group. #The 21 Vβ families studied (left-right) were Vβ1, 2, 3, 5.1, 5.2, 5.3, 7, 8, 9, 11, 12, 13.1, 13.6, 14, 16, 17, 18, 20, 21.3, 22, and 23.

CD8 expression in T-cell expansions.

T-cell expansions from 27 age-matched donors were compared with 22 patients with MM. The data of patients with MM have been published previously5 and were reanalyzed and reported again here for comparison. Cells were gated for either CD8−CD3+ (panels A through D) or CD8+CD3+ T cells (panels E through H) before calculation of the percentage of cells expressing each Vβas a function of either total CD3+ T cells (panels A through B and E through F), CD8−CD3+ (panels C and D), or CD8+CD3+ (panels G and H). Horizontal bars represent 3 SD above the means for the age-matched control group. #The 21 Vβ families studied (left-right) were Vβ1, 2, 3, 5.1, 5.2, 5.3, 7, 8, 9, 11, 12, 13.1, 13.6, 14, 16, 17, 18, 20, 21.3, 22, and 23.

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