Fig. 2.
STI571 prolongs the survival of mice in a murine model of CML.
Lethally irradiated mice were reconstituted with syngeneic BM cells transduced with a replication-defective P210BCR/ABL retrovirus and were then randomized to posttransplantation treatment with either STI571 or placebo. The survival curve depicts the percentage of animals alive at the indicated time point after BM reconstitution (day 0). The number of mice in each arm (N) is also shown.
