Fig. 8.
Fig. 8. The β-GMR but not β-GMRIT confers GM-CSF–dependent proliferation when coexpressed with the defective α/β-GMR-ΔE chimera. / In this experiment, 1 × 105 BaF-3/α/β-GMR (α/β), BaF-3/α/β-GMR-ΔE (ΔE), BaF-3/α/β-GMR-ΔE plus β-GMRIT (clones no. 1 through 5), and BaF-3/α/β-GMR-ΔE plus β-GMR (clones a through c) cells were cultured in the presence of WEHI-CM as a source of mIL-3, huGM-CSF (20 ng/mL), or the monoclonal anti–α-GMR S-20 antibody as indicated. Viable cells were counted after trypan blue staining on day 3.

The β-GMR but not β-GMRIT confers GM-CSF–dependent proliferation when coexpressed with the defective α/β-GMR-ΔE chimera.

In this experiment, 1 × 105 BaF-3/α/β-GMR (α/β), BaF-3/α/β-GMR-ΔE (ΔE), BaF-3/α/β-GMR-ΔE plus β-GMRIT (clones no. 1 through 5), and BaF-3/α/β-GMR-ΔE plus β-GMR (clones a through c) cells were cultured in the presence of WEHI-CM as a source of mIL-3, huGM-CSF (20 ng/mL), or the monoclonal anti–α-GMR S-20 antibody as indicated. Viable cells were counted after trypan blue staining on day 3.

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