Fig. 6.
Fig. 6. The β-GMR supports but the β-GMRITinhibits proliferation mediated by α/β-GMR. / BaF-3/α/β-GMR (black square), BaF-3/α/β-GMR plus β-GMR (triangle), and BaF-3/α/β-GMR plus β-GMRIT (clones no. 3 through 5) cells were seeded at increasing concentrations of huGM-CSF, as indicated, or in the presence of mIL-3 (10 ng/mL). GM-CSF–mediated proliferation was normalized in comparison with proliferation induced by mIL-3 (100%). The background-corrected fluorescence intensity in response to mIL-3 was between 106 and 133, and background fluorescence without cytokine stimulation was lower than 4 relative fluorescence units.

The β-GMR supports but the β-GMRITinhibits proliferation mediated by α/β-GMR.

BaF-3/α/β-GMR (black square), BaF-3/α/β-GMR plus β-GMR (triangle), and BaF-3/α/β-GMR plus β-GMRIT (clones no. 3 through 5) cells were seeded at increasing concentrations of huGM-CSF, as indicated, or in the presence of mIL-3 (10 ng/mL). GM-CSF–mediated proliferation was normalized in comparison with proliferation induced by mIL-3 (100%). The background-corrected fluorescence intensity in response to mIL-3 was between 106 and 133, and background fluorescence without cytokine stimulation was lower than 4 relative fluorescence units.

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