Southern blot analysis of the c-myc locus in SIV-associated lymphomas. DNA samples were digested with EcoRI and hybridized with the pMC41-3DC probe covering the 3rd exon of thec-myc locus. Lanes 1 through 5 are samples of monkeys 4, 208, OD5, 8503, and S1, respectively. The Raji cells (lane 6) carrying the germ line band (12.8 Kd) and a higher rearranged band (<12.8 kd) and monkey PBMC (lane 7) were included as controls.