Morphology of dysplastic AML1-ETO/+ mixed hematopoietic colonies. (A) Abnormal mixed colonies derived fromAML1-ETO/+ fetal liver cells. (B) Cytocentrifuge preparations of cells contained within these colonies. (Left) Numerous hypergranular myeloid cells are seen with frequent abnormal binucleated and trinucleated cells detected. (Right) Illustration of the mixed nature of the colony with maturing erythroid cells, a monocyte, binucleated myeloid precursors, and a dysplastic megakaryoblast.