Schematic representation of the genomic structure ofD^VI type III compared with other alleles of theRHD and RHCE genes. The 10 exons of the Rhesusgenes are symbolized by squares and numbered 1 to 10, the introns are represented by lines. The triangles denote the base substitutions and insertion occurring in intron 1 distinguishing RHD andRHCE. The circles denote the intron 2 polymorphism distinguishing RHD, RHC and RHc. Black symbols represent RHCE-specific sequences, open symbolsRHD-specific sequences. Sequences shared by at least oneRHCE and the wild-type RHD allele are indicated by gray symbols, sequences specific for RHC or for RHE are hatched. The nucleic acid and amino acid sequence accession number ofD category VI type III was Z97026.