Fig. 3.
Survival (30 days) of irradiated recipients (Ly5.1) transplanted with donor (Ly5.2)-derived BM cells or PBMNC from control or FL-treated mice. Donor mice were treated once daily for 10 days with 1 μg MSA (control PBMNC and BM) or MSA plus 10 μg FL SC. Donor PBMNC (5 × 105 or 1 × 105 cells/mouse) or BM (2 × 105 cells/mouse) were injected IV 3 to 4 hours postirradiation into recipient mice (10 to 15 mice per group). There was significantly greater survival from mice reconstituted with control BM and PBMNC (5 × 105 cells) from FL or FL + G-CSF–treated mice when compared with irradiation control or control PBMNC groups (see Results).
