Fig. 1.
Fig. 1. Platelet counts and anti-rhML antibody titers for dogs repeatedly administered daily rhML. The schedule for dosing is shown at the top of the panel. Dog B was also administered recombinant human IL-6 for the days shown. Antibody (Ab) titers are expressed as the lowest titer of serum having an inhibitory concentration more than the IC50 for a standard antibody.

Platelet counts and anti-rhML antibody titers for dogs repeatedly administered daily rhML. The schedule for dosing is shown at the top of the panel. Dog B was also administered recombinant human IL-6 for the days shown. Antibody (Ab) titers are expressed as the lowest titer of serum having an inhibitory concentration more than the IC50 for a standard antibody.

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