Improvement of the recovery of hematopoietic cells with AcSDKP in DOX-treated mice. AcSDKP was administered continuously by minipumps at a rate of 100 ng/h for 72 hours beginning 48 hours before the first DOX injection. In each experiment, mice (n = 5) were killed at different times, bone marrow was collected and pooled, and colony assays were performed: (A) CFU-GM, (B) HPP-CFC, (C) CFU-S. Results are expressed as the mean ± standard deviation of three (B and C) or four (A) experiments. Asteriks indicate significant differences between experimental and control groups: *P < .05; **P < .01 (Student's t-test).