Effects of sLe^x and CGP69669A on surgically stimulated L-selectin–dependent leukocyte rolling in vivo. Mouse cremaster muscle was prepared for intravital microscopy and superfused with bicarbonate buffer for 60 minutes to produce rolling that was partially L-selectin–dependent. Shown are the effects of treatment with sLe^x (100 mg/kg), CGP69669A (100 mg/kg), and anti–L-selectin antibody Mel 14 (10 μg). Data are presented as the mean ±SEM of values from at least 9 venules from 4 mice per treatment group. **Significantly different from control (P < .01).