Fig. 4.
![Fig. 4. Induction of erythroid colony formation from fetal liver CFU-E progenitors requires the expression of the EpoR. Day-12.5 fetal liver cells dissected from EpoR−/− embryos (A) or from wild-type embryos (B) were infected with viruses encoding β-galactosidase (control), gp55-P, gp55-A, and murine EpoR. The retroviral vector used is indicated (SFFV or pBABE). Cells were assayed in CFU-E assays in the absence or presence of EPO or (in the right-most panel of [A]) in the presence of Epo and SF. Data represent the average of two experiments, each performed in duplicate; the variation was less than 20%.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/91/4/10.1182_blood.v91.4.1163/4/blod4044104.jpeg?Expires=1724243716&Signature=YREG0JuRUoz8lQNGQCrbvvR3f~fHznjBOnRDoUgCQ64BngCnb4qWbGwXWG0z~ThKr7-VQL8yskZjyVVJn9VavjPVLbYDx13MV-5iBrS6vG3cc61tx5BDOybzcQAjfe4HwbZ34BfSp1lYJQFgn5ophCQtlVFRc~DbHIIk8LgyqqUOVFOuvIdeMQWNOjspOeKavnkYsJOazJnsbXh34dhjt5tmL9oiYKMa7YvsiGNgBjXyjYDFYwaspuIBFB5RgPLEDrPoSCFiC4sOKW0-T1xfS9ZKXmUxh7~31R0R02yQV~fjhsSoq2qmH3xpmbB3F5dZ25KxLyFjbWQXlkWC~cpA9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Induction of erythroid colony formation from fetal liver CFU-E progenitors requires the expression of the EpoR. Day-12.5 fetal liver cells dissected from EpoR−/− embryos (A) or from wild-type embryos (B) were infected with viruses encoding β-galactosidase (control), gp55-P, gp55-A, and murine EpoR. The retroviral vector used is indicated (SFFV or pBABE). Cells were assayed in CFU-E assays in the absence or presence of EPO or (in the right-most panel of [A]) in the presence of Epo and SF. Data represent the average of two experiments, each performed in duplicate; the variation was less than 20%.
