Comparison of FBF and t-PA net release between infusion arm (▪) and control arm (○) during constant-rate infusion of DDAVP (70 ng/min for 20 minutes) in 4 healthy male subjects. Means and SEM error bars. Both FBF and t-PA net release increased significantly in the infusion arm as compared with the control arm (ANOVA, time × treatment interaction: P < .01 for both).