Fig. 1.
![Fig. 1. Proliferation of MO7e cells in response to SCF correlates with c-kit receptor dimerization detected by FRET. MO7e cells were washed to remove GM-CSF and resuspended at a concentration of 1 × 105 cells/mL in IMDM suppplemented with 10% FCS and various concentrations of SCF (0 to 1,000 ng/mL; •), or 104D2 (0.5 μg/mL). After a 3-day incubation at 37°C, the number of viable cells was counted. The data represent the mean (± standard error of mean [SEM]) of triplicate values from one experiment. The wells supplemented with 104D2 contained 1.1 ± 0.2 × 105 MO7e cells/mL on day 3.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/91/3/10.1182_blood.v91.3.898/3/blod4031801.jpeg?Expires=1724226870&Signature=IcQfrz520yr16slGDKTHLxw0QG3WrH77Je0DizNnz0fuWOQynqfMyTYxQUlaKMVB1pSddfTduhFKvz8tF9G41CESdZd6-1Exe9~-k7uU9arQxV~F0GsDQo~JcL2U9H4nfPig2dF-bUtuvTEHxX5jZM34cLpHy4AOv6pkbwcJEyPqS9e8rB7Lq~uuGPiSj5HLwqSMkAamUNm4ZHSFga76TS7AVaoZl4ZnNMike~kuIMDXi7Pwc7QV200jCEUw81P1XBHzlXxQCNqZoA9hWXsY2DpQV8qco2FyhwwoCX5paZ93R~VL5TZYd8IupA0hmqxWv3-onfLN4-GTC13QVGIAAQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Proliferation of MO7e cells in response to SCF correlates with c-kit receptor dimerization detected by FRET. MO7e cells were washed to remove GM-CSF and resuspended at a concentration of 1 × 105 cells/mL in IMDM suppplemented with 10% FCS and various concentrations of SCF (0 to 1,000 ng/mL; •), or 104D2 (0.5 μg/mL). After a 3-day incubation at 37°C, the number of viable cells was counted. The data represent the mean (± standard error of mean [SEM]) of triplicate values from one experiment. The wells supplemented with 104D2 contained 1.1 ± 0.2 × 105 MO7e cells/mL on day 3.
