Inhibition of p21E reactivity by purified BA21. Reactivity towards purified p21E protein obtained in the absence (▪) or presence of 1 μg of added BA21 (▨) or 1 μg nonrecombinant sj26 protein (□). Sera tested were from BA21 reactive CD3-LGDL patients (LGL), BA21 negative blood donors (NEG DNR), BA21 reactive blood donors (POS DNR) and a BA21 reactive, HBV core antibody positive donor (CORE + DNR). All sera were diluted 1/100 in BLOTTO and the assay was performed as described in Materials and Methods. The bars represent the mean of two determinations and the error bar indicates the absorbence obtained from the higher replicate.