Analysis of four polymorphic markers in introns A, B, E, and M of the FXI gene. SSCP in intron A: an autoradiogram shows samples of a heterozygote for alleles 1/2 (lane 1), a homozygote for allele 2 (lane 2), and a homozygote for allele 1 (lane 3). CA repeat in intron B: an autoradiogram shows samples of a heterozygote 2/4 (lane 1), a homozygote for allele 3 (lane 2), a heterozygote 1/2 (lane 3), a heterozygote 2/4 (lane 4), and a homozygote for allele 2 (lane 5). RFLP in intron E: an ethidium bromide–stained agarose gel shows in lane 1 the pBR322 DNA/Alul marker, samples of homozygotes for allele 2 (lane 2) and allele 1 (lane 3), and a sample of a heterozygote for alleles 1/2 (lane 4). AT repeat in intron M: an autoradiogram shows samples of a heterozygote for alleles 1 and 3 (lane 1), a homozygote for allele 3 (lane 2), a heterozygote for alleles 2 and 4 (lane 3), a homozygote for allele 3 (lane 4), a heterozygote for alleles 3 and 4 (lane 5), and a heterozygote for alleles 1 and 3 (lane 6).