Fig. 1.
Fig. 1. Deduced amino acid sequences of VH-Cγ and VH-Cμ transcripts from patients' tumor cells synthesizing both IgG and IgM isotypes. (A) Cases with both IgM and IgG serum parapoteins. (B) Cases with IgG serum paraproteins only. Comparisons are made with the closest germ line VH genes. Upper case, replacement mutations; lower case, silent mutations. Replacement mutations in JH are underlined.

Deduced amino acid sequences of VH-Cγ and VH-Cμ transcripts from patients' tumor cells synthesizing both IgG and IgM isotypes. (A) Cases with both IgM and IgG serum parapoteins. (B) Cases with IgG serum paraproteins only. Comparisons are made with the closest germ line VH genes. Upper case, replacement mutations; lower case, silent mutations. Replacement mutations in JH are underlined.

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