Fig. 1.
![Fig. 1. Effect of immobilized Lym-2 on the proliferation of various B-cell lymphoma cell lines. Lymphoma cell lines were incubated with Lym-2 or mIgG1 with immobilization by prior coating plates by goat-antimouse IgG1. Three days later, effects on growth were evaluated by incorporation of [3H]-thymidine. Soluble Lym-2 exerted no effect on proliferation of these lymphoma cell lines (data not shown). However, immobilized Lym-2 significantly inhibited the proliferation of (A) RL, (B) TU-2C, (C) Raji, (D) Michel, (E) Daudi, and (F ) DB cell lines (P < .05) with optimal inhibition of thymidine incorporation (39% to 65%) occurring at 1 μg/mL of Lym-2.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/8/10.1182_blood.v90.8.3160/4/bl_0029f1.jpeg?Expires=1722721918&Signature=tDV3Af3zCqTbUfbV50kCsslyuoFZJkuqCnX7X6Ty446-mQP8kRab6L~5Y3pD2QMnx-ItZghldAdf9ylryORM31OSILTsAezBSeb5edkdO4VYw71VpKu0mGIvJOx2Uxsy2CcUgObpRssbc2bTI-LcIMTGKq2V2X-GAiaHuxtTab~oIjRM3G3bWpGfbCpI8Y83OMF270Ou5xaFhrMW8piyoFp5ffzqFhsnHcyZ3dRDDnpV7VHEKYYl32XG8UoWVMNbW9LwFUvkZ5NP0rQqiBjY9DgbrQAuipRnoez5n7~CjfBz1KPqVPUPUnlm3MhZvWUFH7Wpz69IwNkzCH~F5prUWg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of immobilized Lym-2 on the proliferation of various B-cell lymphoma cell lines. Lymphoma cell lines were incubated with Lym-2 or mIgG1 with immobilization by prior coating plates by goat-antimouse IgG1. Three days later, effects on growth were evaluated by incorporation of [3H]-thymidine. Soluble Lym-2 exerted no effect on proliferation of these lymphoma cell lines (data not shown). However, immobilized Lym-2 significantly inhibited the proliferation of (A) RL, (B) TU-2C, (C) Raji, (D) Michel, (E) Daudi, and (F ) DB cell lines (P < .05) with optimal inhibition of thymidine incorporation (39% to 65%) occurring at 1 μg/mL of Lym-2.
