Fig. 5.
Correlation of FcγRI expression by neutrophils with phagocytosis by neutrophils of S aureus opsonized with complement-depleted pooled human serum. FcγRI expression by neutrophils from study subjects was determined by direct immunostaining before and after in vivo rhIFN-γ administration (0.05 mg/m2 SC daily for 2 days). Correlation of FcγRI expression by neutrophils with their ability to perform phagocytosis of HI-PHS–opsonized S aureus BioParticles was determined by regression analysis. FcγRI expression by neutrophils correlated directly with ability to ingest HI-PHS–opsonized S aureus (r = .8, P < .05).
