Rejection of GM-AML cells is not T-cell–dependent. (A) Swiss nu/nu mice, in groups of 6, were injected IV with 10⁵GM-AML cells (□) or 10⁵ mock-infected control cells (•). The former group rejected their tumor, whereas the latter group developed lethal leukemia. (B) SJL/J mice, in groups of 6, were irradiated (600 cGy TBI) and injected 2 days later with 10⁵GM-AML cells (○) or mock-infected control cells (▵). Both groups of SJL/J mice developed lethal leukemia.