Fig. 11.
Evolution of functions during DC subpopulation maturation. The figure represents parameters of DC activities as a function of time. MFI of CD86 illustrates the progression of DC maturation. FITC dextran illustrates the capacity of antigen uptake. NSE illustrates the lysosomal activity. T-cell alloreaction illustrates the capacity to activate naive T cells. B-cell differentiation illustrates the capacity to induce naive B-cell differentiation in response to IL-2. To plot the different parameters on a same scale, values were calculated as the following ratio: (experimental value/maximal value) × 100; the maximal value being the maximal value obtained with either CD1a or CD14 populations. (A) The evolution of the CD1a-derived cells activities. (B) The evolution of the CD14-derived cells activities.

Evolution of functions during DC subpopulation maturation. The figure represents parameters of DC activities as a function of time. MFI of CD86 illustrates the progression of DC maturation. FITC dextran illustrates the capacity of antigen uptake. NSE illustrates the lysosomal activity. T-cell alloreaction illustrates the capacity to activate naive T cells. B-cell differentiation illustrates the capacity to induce naive B-cell differentiation in response to IL-2. To plot the different parameters on a same scale, values were calculated as the following ratio: (experimental value/maximal value) × 100; the maximal value being the maximal value obtained with either CD1a or CD14 populations. (A) The evolution of the CD1a-derived cells activities. (B) The evolution of the CD14-derived cells activities.

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