Fig. 5.
![Fig. 5. Influence of pretreatment with SDZ MRL 953 on the endotoxin-induced release of G-CSF and changes in neutrophil counts in cancer patients. (A) Serum levels of G-CSF and (B) percentage changes of neutrophil granulocytes in patients after an intravenous bolus injection of LPS (2 ng/kg) administered 72 hours after the last of seven injections of (•) SDZ MRL 953 (18.0 to 39.6 μg/kg, n = 14 [A] and n = 10 [B]) or (▿) vehicle control (n = 5). Data are expressed as the mean ± SEM. *P < .05, **P < .01 between groups.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/4/10.1182_blood.v90.4.1673/3/bl_0035f5b.jpeg?Expires=1723361311&Signature=TAlJv9vW4~vlUZi~ihSKmBCrjLsZk~h8LkcgSVc7GCJhcrfVjCr6-VCAwtd1r43UFGETulmyhRvPf9TbxD1eYvkCTg861YqX63U01i~1H2xNDQVGKlARxeLu-lvmMB9aYwfDuFdPxmKugT3jG~t11jXZmEK6saxKzaH83widnE6~j5exKWI6OgFaBW6FdDKZ6lbIyI9Urt60KF2dz594SM2h0uezGI5cMJsLMRkM5S7rCtGkMayDHfTqGDhPDZAHFZJG17c~TxJowL8ZM4~eJJrLuhXppR582T4tXpKv5DCha8PIYRwEtNRxnm76sz8DxUhE0u-GZDvVVv6WxHMjqw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Influence of pretreatment with SDZ MRL 953 on the endotoxin-induced release of G-CSF and changes in neutrophil counts in cancer patients. (A) Serum levels of G-CSF and (B) percentage changes of neutrophil granulocytes in patients after an intravenous bolus injection of LPS (2 ng/kg) administered 72 hours after the last of seven injections of (•) SDZ MRL 953 (18.0 to 39.6 μg/kg, n = 14 [A] and n = 10 [B]) or (▿) vehicle control (n = 5). Data are expressed as the mean ± SEM. *P < .05, **P < .01 between groups.
