Schematic diagram of FXII gene promoter and the location of four putative binding site for HNF-3. Location of HNF-3 putative binding sites on the 5′-flanking region of FXII gene. Abbreviations for nucleotides are as follows: R = G or A; Y = C or T. The mismatches from the consensus sequence deduced for HNF-3 binding sites48 are underlined.