Fig. 1.
CD4 ligation with gp160 or CD4XL with gp160 and anti-gp160 induces tyrosine phosphorylation of various cellular substrates: CD4+ T cells were treated with gp160 alone or with gp160 plus anti-gp160. Cell lysates were precleared and immunoprecipitated with antibodies to substrates p56lck, p59fyn, ZAP-70, PLC-γ1 (145 kD), and p95vav as indicated and immunoblotted with either the specific antibody or with antiphosphotyrosine antibody (4G10).

CD4 ligation with gp160 or CD4XL with gp160 and anti-gp160 induces tyrosine phosphorylation of various cellular substrates: CD4+ T cells were treated with gp160 alone or with gp160 plus anti-gp160. Cell lysates were precleared and immunoprecipitated with antibodies to substrates p56lck, p59fyn, ZAP-70, PLC-γ1 (145 kD), and p95vav as indicated and immunoblotted with either the specific antibody or with antiphosphotyrosine antibody (4G10).

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal