Plasma pharmacokinetic curves after one dose (10 mg) of As₂O₃ in relapsed APL patients. (A) The mean plasma arsenic concentration time curve for eight patients. Bar, SD. (B) Pharmacokinetic curves obtained on day 1 and day 30 of As₂O₃ remission induction in patient no. 6. (C) Pharmacokinetic curves determined on day 1 of remission induction and day 1 of consolidation therapy in patient no. 13.